September 27, 2023


Healthy Life

Roland Griffiths, Ph.D. — Life’s Final Glide Path, An Surprising Stage IV Analysis, Going through Demise, How Meditation and Psychedelics Can Assist, and The Artwork of

11 min read

“I might’ve claimed to be fairly awake previous to the most cancers analysis. I’m rather more awake now. There’s no purpose that we are able to’t all get up. That’s the overarching message that I need to broadcast is ‘Be a part of me within the celebration, the appreciation of this miracle that all of us discover ourselves in.’”

— Roland Griffiths, Ph.D.

Welcome to a different episode of the Tim Ferriss Present. It is a very significant episode to me. It’s most likely essentially the most vital interview that I’ve recorded within the final 12 months, and it’s with certainly one of my favourite folks and certainly one of my favourite scientists on the earth: Roland Griffiths, PhD.

Roland has not too long ago been recognized with what may be very possible terminal stage-four most cancers. If you happen to’ve ever discovered your self impressed by somebody who walks the stroll, this episode is value listening to. In going through mortality and doubtlessly going through dying, what Roland has accomplished and is doing, the attitude he’s discovering, and the instruments he’s utilizing, are nothing in need of awe inspiring. His instance is past phrases, and I wished to share that with all of you. 

I hope you discover it as deeply enriching and priceless as I did. It’s a very tender dialog at factors, a really humorous dialog, and in some ways, a really profound dialog.

To be taught extra about Roland’s very formidable challenge to ascertain a world-class psychedelic analysis program—in perpetuity—to advance human flourishing and well-being, please go to

Presently, Roland has acquired pledges totaling about $14M. Because of this he’s $6M in need of the $20M goal, adequate to help the total analysis program. To donate, please go to and click on “Donate.”

For extra details about establishing a serious reward, please contact Mike DeVito, the Senior Affiliate Director of Improvement at [email protected] or name him at (443) 278-3174. Donors who contribute $1000 or extra and who don’t select to stay nameless might be acknowledged on the web site.

Right here is Roland’s bio:

Roland Griffiths, Ph.D., is a Professor within the Departments of Psychiatry and Neurosciences at Johns Hopkins College, and founding Director of the Johns Hopkins Middle on Psychedelic and Consciousness Analysis. His principal analysis focus in each medical and preclinical laboratories has been on the behavioral and subjective results of mood-altering medication.

His analysis has been largely supported by grants from the Nationwide Institute on Well being, and he’s writer of over 400 scientific publications. He has been a marketing consultant to the Nationwide Institutes of Well being, the World Well being Group, and quite a few pharmaceutical corporations. Roland has performed intensive analysis with sedative-hypnotics, caffeine, and novel mood-altering medication.

In 1994 Roland began an everyday meditation follow that made him inquisitive about sure altered states of consciousness that prompted him in 1999 to provoke the primary examine in a long time to carefully consider the consequences of a excessive dose of a basic psychedelic drug (psilocybin) in wholesome psychedelic-naïve contributors. Subsequent research with psilocybin have been performed in wholesome volunteers, in starting and long-term meditators, and in spiritual leaders. Therapeutic research with psilocybin embody remedy of psychological misery in most cancers sufferers, cigarette smoking dependancy, main melancholy, anorexia nervosa, and Alzheimer’s Illness. Different research have examined non-psychedelic medication that produce altered states of consciousness having similarities to psilocybin. Mind imaging research have examined pharmacological and neural mechanisms of motion of psilocybin.

Roland’s analysis group has additionally performed a sequence of survey research characterizing numerous naturally-occurring and psychedelic-occasioned transformative experiences together with: mystical-type experiences, psychologically difficult experiences, near-death experiences (NDEs), Entity and God-encounter experiences, and experiences to which diminished nervousness, melancholy, and substance use problems are attributed.

Please take pleasure in!

Take heed to the episode on Apple Podcasts, Spotify, Overcast, Podcast Addict, Pocket Casts, Castbox, Google Podcasts, Stitcher, Amazon Musicor in your favourite podcast platform.

#641: Roland Griffiths, Ph.D. — Life’s Final Glide Path, An Surprising Stage IV Analysis, Going through Demise, How Meditation and Psychedelics Can Assist, and The Artwork of Residing a Lifetime of Gratitude

Need to hear one other episode with somebody who’s explored altered states of consciousness with and with out psychedelic compounds? Have a take heed to my dialog with Stan Grof through which we focus on the takeaways from guiding 4,500+ LSD periods, the place and function of wounded healers, limitations and makes use of of conventional psychoanalysis and discuss remedy, the similarities discovered between holotropic breathwork and MDMA, what humanity most wants to beat, and rather more.

#347: Stan Grof, Classes from ~4,500 LSD Classes and Past

What was your favourite quote or lesson from this episode? Please let me know in the comments.




Editor’s observe: timestamps might be added shortly.

  • Roland’s earliest private expertise with psychedelics.
  • Meditation and curiosity in altered states of consciousness.
  • What’s phenomenology?
  • Why early makes an attempt at meditation failed, and what made Roland revisit the follow.
  • Roland’s work with sedative-hypnotics within the late ’70s.
  • Connoisseurs of puff topography.
  • When Roland realized the voice in his head wasn’t his.
  • From meditation to scientific exploration of psychedelics.
  • Entheogens vs. psychedelics.
  • Roland’s preliminary reluctance to experiment with psychedelics.
  • Sasha Shulgin, PiHKAL, and TiHKAL.
  • Invoice Richards.
  • Challenges of the psychedelic trial course of.
  • The outcomes of Roland’s first main psychedelic examine.
  • Pre-existing literature on mystical experiences.
  • Roland’s newer psychedelic experiences.
  • Why isn’t Roland devastated by his terminal analysis?
  • Ego dissolution and nervousness discount.
  • The actual goal of this dialog.
  • A rundown of Roland’s analysis and the way he’s dealing with it.
  • “Each day is Thanksgiving.”
  • Gratitude meditation, liver embolization, and different mortality navigations.
  • Satcitananda.
  • Eliciting 5-MeO “placebo” experiences with out psychedelics.
  • How does Roland relate to dying?
  • How family members may be supportive of somebody dealing with a terminal analysis.
  • Perception modifications related to psychedelic use.
  • Ideas from the crossroads of the quantum, the paranormal, and the psychedelic.
  • The endowed professorship and its foreseeable areas of analysis.
  • David Yaden.
  • Is there a contingency if Usona ceases to exist?
  • Roland’s present prognosis.
  • Roland’s parting ideas of gratitude and the highway forward.


“I don’t know what occurs [after death]. However what I do know is that this reward we’ve been given to be these sentient creatures, strolling round, being conscious that we’re conscious with just a bit little bit of contemplation, a miracle will not be an inappropriate descriptor of the place we discover ourselves. How this has come about and why we’ve been gifted with this chance is unknown to us, nevertheless it ought to be a supply of unimaginable gratitude and pleasure and celebration.”

— Roland Griffiths

“What’s attention-grabbing to me now in the place I discover myself with this terminal most cancers analysis, and reflecting on how I’m managing that personally, and as we’ve mentioned, the sense is that I’ve a way of equipoise and steadiness, curiosity, marvel, gratitude — a way of celebration for the preciousness of life. … How do you account for that? One would possibly suppose {that a} terminal analysis could be devastating. I can’t probably know how one can account for the way I’ve managed that analysis over these first eight months, however what I might extremely suspect is that it has so much to do with my lengthy historical past of meditation follow, and it’s knowledgeable by a few of the experiences that I’ve had with psychedelics. So with regard to the meditation, there’s an actual coaching of the character of thoughts — watching one’s thoughts de-identifying from the voice within the head and making optimum selections about how one needs to proceed in a single’s life.”

— Roland Griffiths

“Peculiarly, my expertise has been certainly one of celebration, and my spouse has joined me in that. I deeply need to share that with folks as a result of there’s no purpose that all of us shouldn’t be celebrating. It’s taken me a terminal most cancers analysis to totally awake to that. I might’ve claimed to be fairly awake previous to the most cancers analysis. I’m rather more awake now. There’s no purpose that we are able to’t all get up. That’s the overarching message that I need to broadcast is: be part of me within the celebration, the appreciation of this miracle that all of us discover ourselves in.”

— Roland Griffiths

“It actually is that this invitation to face what initially seems to be the darkish facet of issues, essentially the most horrifying issues. I must say terminal most cancers analysis would possibly properly qualify as emblematic of such an expertise. Maybe psychedelic experiences that had unfavorable, valenced qualities to them, and the way I realized to navigate these, may have been crucial to me in how I got here to search out myself navigating the analysis.”

— Roland Griffiths

“Each day I get up is Thanksgiving.”

— Roland Griffiths

“Whenever you begin listening to that voice [in your head] and realizing it’s not you, then swiftly the sport begins altering.”

— Roland Griffiths

“An image of the guru sat there. I used to be this image, and swiftly, the eyes grew to become alive. I used to be trying into the image, and I used to be trying into these eyes that have been trying proper again at me. And as I appeared extra intently, I noticed I used to be trying in my very own eyes. And with that understanding, and this wouldn’t be generally held inside the custom, I acknowledged that I used to be the guru, that I used to be no completely different than the guru, that the guru was only a mirror of who you might be. And with that sort of understanding, I used to be in a position to be part of the group in reverence to the guru as a result of it was in reverence to this deeper interconnectedness that the guru was reflecting again. And I used to be in a position to pranam, bow, in entrance of the guru as a result of I used to be bowing to myself. And in order that shifted a body of reference that allowed me to interact in that group. After which I began extra severe every day meditation practices that I’ve continued ever since.”

— Roland Griffiths

“Science itself is solely open-ended and agnostic. All it’s making an attempt to do is locate out what’s true.”

— Roland Griffiths

“The enjoyable of science is you’ll be able to observe your hunches.”

— Roland Griffiths


The Tim Ferriss Present is one of the preferred podcasts on the earth with greater than 900 million downloads. It has been chosen for “Better of Apple Podcasts” 3 times, it’s typically the #1 interview podcast throughout all of Apple Podcasts, and it has been ranked #1 out of 400,000+ podcasts on many events. To take heed to any of the previous episodes free of charge, take a look at this web page.

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